![]() For the adult female, with her generally lower muscle mass, the normal range is 0.5 to 1.1 mg/dl, or 44 to 97 μmol/L by the enzymatic method.Ĭopyright © 1990, Butterworth Publishers, a division of Reed Publishing. For the adult male, the normal range is 0.6 to 1.2 mg/dl, or 53 to 106 μmol/L by the kinetic or enzymatic method, and 0.8 to 1.5 mg/dl, or 70 to 133 μmol/L by the older manual Jaffé reaction. The normal serum creatinine ( sCr) varies with the subject's body muscle mass and with the technique used to measure it. This is equivalent to serum urea nitrogen content of 8 to 25 mg per 100 ml and will be recognized by clinical physicians as the normal range of blood urea. In contrast, the rugged rancher who eats in excess of 125 g protein each day may have a normal BUN of 20 mg/dl. Her higher glomerular filtration rate (GFR), expanded extracellular fluid volume, and anabolism in the developing fetus contribute to her relatively low BUN of 5 to 7 mg/dl. A BUN of 15 mg/dl would represent significantly impaired function for a woman in the thirtieth week of gestation. The range is wide because of normal variations due to protein intake, endogenous protein catabolism, state of hydration, hepatic urea synthesis, and renal urea excretion. The normal range of urea nitrogen in blood or serum is 5 to 20 mg/dl, or 1.8 to 7.1 mmol urea per liter. The BUN, then, is roughly one-half (28/60 or 0.446) of the blood urea. In Europe, the whole urea molecule is assayed, whereas in the United States only the nitrogen component of urea (the blood or serum urea nitrogen, i.e., BUN or SUN) is measured. Both are relatively small molecules (60 and 113 daltons, respectively) that distribute throughout total body water. 1 3 years, 11 36 mg/dL, 1.8 6.0 mmol/L BUN (Blood urea nitrogen) in serum/. Creatinine is the product of muscle creatine catabolism. Global, 17 43 mg/dL, 2.8 7.2 mmol/L Children. The normal adult range is 6 to 25, with 15.5 being the optimal value. Urea is the primary metabolite derived from dietary protein and tissue protein turnover. A blood urea nitrogen (BUN) test measures the amount of nitrogen in your blood that comes from the waste product urea. The BUN/creatinine ratio is a good measurement of kidney and liver function. We measured the variables also in 315 cases of sex-matched young control subjects (male, 139 female, 176). Urea and creatinine are nitrogenous end products of metabolism. To estimate normal ranges of blood urea nitrogen (BUN) and serum creatinine (Cr) levels in the aged, we measured BUN and Cr levels in 332 cases of apparent-healthy elderly subjects (male, 152 female, 180) aged 70 years or more. ![]()
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